Dietary Intake of Mother in Childbearing Age with BMI <18.5 kg/m2 and has Heterozygous Variant D327N SHBG Genotype (w/v)

Parwanto, Edy ML and Senjaya, Hardy (2017) Dietary Intake of Mother in Childbearing Age with BMI <18.5 kg/m2 and has Heterozygous Variant D327N SHBG Genotype (w/v). International Journal of Community Medicine and Public Health, 4 (2). pp. 409-417. ISSN 2394-6040

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Abstract

Background: Body mass index (BMI) determined by genetic and environmental factors. One of the genetic factors that determine the BMI is a genetic polymorphism of sex hormone binding globulin (SHBG), whereas the intake of nutrients is one of the environmental factors. The objective: investigate to macronutrient intake of mother in childbearing age with BMI <18.5 kg/m2 and has heterozygous variant D327N SHBG genotype (W/v). Methods: Anthropometric measurement, genotyping of D327N SHBG gen exon 8, and three days repeated food recall and record was done for all subjects. BMI in the group I 16 to <17 kg/m2 and group II 17 to <18.5 kg/m2. For all subjects in both groups has heterozygous variant D327N SHBG genotype (W/v). Results: mother in chieldbearing age with BMI <18.5 kg/m2 and has heterozygous variant SHBG genotype (W/v) is undernutrition. Seventy two percent of the total subjects including type I of chronic energy deficiency (CED), and 28% as type II of CED. Protein, fat and carbohydrate intake and mid-upper arm circumference (MUAC) in the group I was lower than group II (p<0.05), while muscle mass in the group I did not different compare to group II (p>0.097). Conclusions: Mother in childbearing age with BMI <18.5 kg/m2 and has heterozygous variant D327N SHBG genotypes (W/v) shows that the lower of protein, fat and carbohydrate intake then CED status is getting low.

Item Type: Article
Subjects: Q Science > QH Natural history > QH426 Genetics
Divisions: Faculty of Medicine > Undergraduate Program in Medicine
Depositing User: FK Usakti
Date Deposited: 26 Oct 2017 03:03
Last Modified: 31 Oct 2017 01:39
URI: http://libprint.trisakti.ac.id/id/eprint/359

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